Hands-On Model of the Principle of Isotope Dilution Analysis for Use in an Interactive Teaching and Learning Classroom Exercise

A simple hands-on model for illustrating the concept of isotope dilution analysis (IDA) has been devised. The consists two sets beads different sizes, with one set representing atoms analyte and other solvent water molecules. Phase separation is mimicked by sieving beads, results are detected according to color beads. In this paper, following three IDA methods illustrated using model: (1) direct IDA, (2) substoichiometric (3) IDA-assisted neutron activation analysis. was demonstrated a small group graduate students previous knowledge nuclear chemistry, response from an inquiry held after demonstration good. It suggested that can be used in dry chemistry laboratory exercise demonstrate methodological differences between methods, without need costly radioisotopes or irradiation facilities. also as tool engaging meta-modeling activities.